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IV NAD+ Therapy

Turn back the clock with NAD+

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What is NAD+?

NAD is the abbreviation for a compound called nicotinamide adenine dinucleotide, which is well-known for its critical role in energy production. Recently, many studies have been performed to explore the role of NAD in signaling pathways within the cells of our bodies. With involved roles in not just energy production, but also in the proper functioning of the immune system and cell survival, NAD has been suggested as a possible therapeutic target for the control of multiple diseases including age-associated disorders, neurodegenerative diseases, and mental disorders.

Levels of NAD+, a form of NAD, naturally decline within the body as we age as a result of DNA damage from the accumulation of toxins or ultraviolet exposure. This decrease results in altered metabolic states and increased disease susceptibility. It has been predicted that restoring NAD+ levels can promote general health and even extend the human lifespan. This hypothesis has prompted many recent studies, many of which have shown NAD+ supplementation to increase the body’s resilience to many different diseases.

Why NAD+ IV Therapy?

A host of different NAD+ supplementation methods have been studied to date, including oral supplementation of NAD precursors such as vitamin B34, nicotinamide riboside (NR), nicotinamide mononucleotide (NMN), and nicotinamide1. However, as opposed to supplementation via oral means, intravenous administration of nutrients is known to result in higher concentrations of NAD+ in the bloodstream5. In addition, attempts to increase the levels of NAD+ via the ingestion of NAD precursors is highly limited by the processing of these molecules into available NAD+2.

At Hudson Medical + Wellness, physician-guided intravenous NAD+ supplementation can provide a more direct and effective approach to increase NAD+ levels.

How does NAD+ Work?

A family of NAD+-dependent proteins called sirtuins play a central role in translating NAD+ levels to the regulation of key cellular processes like metabolism, DNA repair, or stress response3. The actions of sirtuins mediate broad functions involved in the regulation of aging and longevity.

In mammals, there are seven sirtuin families, SIRT1-7, that function in various compartments within human cells. The activation of sirtuins generally triggers the production of proteins that enhance metabolic efficiency and increase resistance to cell and tissue damage by toxins6.

By increasing antioxidant activity and activating DNA damage repair proteins, sirtuins have been shown to promote longevity in organisms ranging from yeast to mice and to mitigate diseases of aging in mouse models.

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